Antihemophilic Globulin Consumption During Blood Coagulation

[antihemophilic Globulin Consumption during Blood Coagulation].

Plasma activity of antihemophilic globulin (AHG) and other coagulation factorsin Swiss type of agammaglobulinemia.

T HE SITE of synthesis of antihemophilic globulin ( AHG, Factor VIII ) and the factors which regulate its plasma concentration are largely unknown. AHG is probably stored somewhere in the body since both adrenalin and cxercise increase the circulating level within minutes. Increased AHG activity has been reported in pregnancy,”2 come malignant diseases,3 trauma and postoperative states,4 hypert...

Studies in Blood Coagulation: the Coagulation Properties of Certain Globulin Fractions of Normal Human Plasma in Vitro.

Blood coagulation and the practical significance of recent advances in knowledge of prothrombin and Ac-globulin.

An attempt is made to describe the nature of the chemical interactions participating in blood clotting. In the laboratory, thrombin can be derived directly from prothrombin without the physiologic activators calcium, thromboplastin, Ac-globulin, and platelet derivatives. The newly recognized clotting factor, Ac-globulin, is essential for normal physiologic hemostasis. Plasma Ac-globulin concent...

The survival of factor VIII (antihemophilic globulin) and factor IX (plasma thromboplastin component) in normal humans.